U3.5 -189
No more than 3 goals will be scored in the match with odds of -189X2 120
FSV Mainz 05 to win or drawUnder 3.5 -189
No more than 3 goals will be scored in the matchNo 123
At least one team is not expected to scoreX2&U5.5 142
Away win/draw and under 5.5 goals
0:1
Preview
The Bayer Leverkusen vs FSV Mainz 05 prediction for Saturday, 28 February 2.26 (kickoff 14:30 GMT) comes with a familiar Bundesliga plot: a bigger-budget home side trying to keep its top-four hopes alive, and a stubborn visitor doing everything possible to stay comfortably above the relegation noise. Leverkusen arrive 6th on 39 points, while Mainz sit 13th with 22, and the table gap feels real even before you look at the squad values (€4.25.76m vs €142.80m).
Leverkusen under Kasper Hjulmand have largely stuck to flexible shapes like 3-4.25-1 and 4-3-3, looking to own the ball and pin teams back. The problem this week is that possession is easier to plan for than personnel. A defensive injury list led by Loïc Badé (thigh) and goalkeeper Mark Flekken (medial ligament) forces a few compromises, and it may mean an uncommon starting opportunity for Tim Oermann. Further forward, Nathan Tella, Eliesse Ben Seghir, and Malik Tillman are also missing, while Lucas Vázquez is a major doubt after being forced off in midweek, and Ibrahim Maza is racing the clock but has a better chance to feature.
Mainz, coached by Urs Fischer, tend to be more conservative by design. His 3-5-2 usually prioritizes spacing, second balls, and staying connected between the lines, with Nadiem Amiri’s craft and Lee Jae-sung’s running doing a lot of the heavy lifting in transition. Mainz are not arriving at full strength either: Benedict Hollerbach, Andreas Hanche-Olsen, Stefan Bell, and goalkeeper Robin Zentner are out, while illness has ruled out Nikolas Veratschnig and Nelson Weiper. The good news is Silvan Widmer returns from suspension and should slot back in wide, which matters a lot in a system that asks wing-backs to provide both width and emergency defending.
For the storyline fans, both teams have recent “don’t tell the odds” moments: Leverkusen’s 0-2 win at Manchester City (priced around 9.5) and Mainz’s 1-2 win at RB Leipzig (around 5.8) are the kind of results that make prediction models sweat a little. Still, the head to head leans Leverkusen: the most recent meeting we have on record (2.25-01-14) ended 1-0 to Leverkusen, and they’ve generally handled Mainz well at home.
Markets lean to the hosts, and it’s easy to see why: home win is priced at 1.72, with the draw at 4.25 and an away win at 4.8. Yet our Bayer Leverkusen vs FSV Mainz 05 Prediction section comes with a warning label: the model’s confidence is low across the board, which is what happens when one team is injury-hit and the other specializes in making matches awkward.
The AI’s best betting tip is Under 3.5 goals at odds 1.53, but with a modest trust rating of 1.9/10. That low trust is important: it suggests the model sees the under as the “least bad” option rather than a slam dunk. The data behind it points to a game where Leverkusen have lots of the ball (possession forecast 65% to 35%) but not endless clear chances.
For the 1x2, the AI-generated call is X2 at 2.18 with a 1.72 trust score, alongside a predicted final score of 0-1 and a half-time 0-0. In plain words: Leverkusen may control territory, but Mainz could be the sharper side in the few moments that matter. If that sounds slightly cheeky given the odds, well, football has never asked for our permission—just our patience.
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Mainz |
18-Oct-25
3:4
| Leverkusen ![]() |
Mainz |
17-May-25
2:2
| Leverkusen ![]() |
Leverkusen |
14-Jan-25
1:0
| Mainz ![]() |
Leverkusen |
23-Feb-24
2:1
| Mainz ![]() |
Mainz |
30-Sep-23
0:3
| Leverkusen ![]() |
Leverkusen |
19-Feb-23
2:3
| Mainz ![]() |
Mainz |
27-Aug-22
0:3
| Leverkusen ![]() |
Mainz |
18-Feb-22
3:2
| Leverkusen ![]() |
Leverkusen |
25-Sep-21
1:0
| Mainz ![]() |
Leverkusen |
13-Feb-21
2:2
| Mainz ![]() |
| 11 Apr | W |
Borussia D
| 0 |
Leverkusen
| 1 |
| 04 Apr | W |
Leverkusen
| 6 |
VfL W
| 3 |
| 21 Mar | D |
Heidenheim
| 3 |
Leverkusen
| 3 |
| 17 Mar | L |
Arsenal
| 2 |
Leverkusen
| 0 |
| 14 Mar | D |
Leverkusen
| 1 |
Bayern Munich
| 1 |
| 11 Mar | D |
Leverkusen
| 1 |
Arsenal
| 1 |
| 07 Mar | D |
Freiburg
| 3 |
Leverkusen
| 3 |
| 04 Mar | W |
Hamburger
| 0 |
Leverkusen
| 1 |
| 28 Feb | D |
Leverkusen
| 1 |
Mainz
| 1 |
| 24 Feb | D |
Leverkusen
| 0 |
Olympiakos
| 0 |
| 16 Apr | Strasbourg |
- | FSV Mainz 05 |
- | |
| 12 Apr | L | FSV Mainz 05 |
0 | SC Freiburg |
1 |
| 09 Apr | W | FSV Mainz 05 |
2 | Strasbourg |
0 |
| 04 Apr | W | Hoffenheim |
1 | FSV Mainz 05 |
2 |
| 22 Mar | W | Mainz |
2 | Frankfurt |
1 |
| 19 Mar | W | Mainz |
2 | Sigma Olomouc |
0 |
| 15 Mar | W | Werder Bremen |
0 | Mainz |
2 |
| 12 Mar | D | Sigma Olomouc |
0 | Mainz |
0 |
| 07 Mar | D | Mainz |
2 | Stuttgart |
2 |
| 28 Feb | D | Leverkusen |
1 | Mainz |
1 |
Germany - Bundesliga| Team | M | G | P | |
|---|---|---|---|---|
| 1 |
Bayern | 29 | 105-27 | 76 |
| 2 |
Borussia | 29 | 60-29 | 64 |
| 3 |
VfB Stuttgart | 29 | 60-38 | 56 |
| 4 |
RB Leipzig | 29 | 56-36 | 56 |
| 5 |
Bayer | 29 | 59-39 | 52 |
| 6 |
1899 | 29 | 57-43 | 51 |
| 7 |
Eintracht | 29 | 54-54 | 42 |
| 8 |
SC Freiburg | 29 | 42-47 | 40 |
| 9 |
FSV Mainz 05 | 29 | 35-44 | 33 |
| 10 |
FC Augsburg | 29 | 36-53 | 33 |
| 11 |
Union Berlin | 29 | 33-50 | 32 |
| 12 |
Hamburger SV | 29 | 32-45 | 31 |
| 13 |
1. FC Köln | 29 | 43-50 | 30 |
| 14 |
Borussia | 29 | 35-49 | 30 |
| 15 |
Werder Bremen | 29 | 32-52 | 28 |
| 16 |
FC St. Pauli | 29 | 25-50 | 25 |
| 17 |
VfL Wolfsburg | 29 | 39-65 | 21 |
| 18 |
1. FC | 29 | 32-64 | 19 |