Mainz
€157.78m
Hoffenheim
€172.55m
X2 -175
Hoffenheim to win or draw with odds of -1752 185
Hoffenheim is expected to win with odds of 185Over 2.5 -145
At least 3 goals will be scored in the matchNo 145
At least one team is not expected to scoreX2&O1.5 -122
Away win/draw and over 1.5 goals
0:1
0:3
Preview
Welcome to our Mainz vs Hoffenheim prediction for the Bundesliga fixture on November 21, 2025. This match at the MEWA Arena promises to be an intriguing contest, with both teams eager to improve their league positions. We’ll break down the latest team news, tactical trends, head to head history, and our AI-powered betting tips, so you can make the most informed decisions.
Mainz and Hoffenheim come into this Bundesliga Round 11 encounter with very different recent fortunes. Hoffenheim currently sit comfortably in 6th place with 19 points, while Mainz are languishing in 17th, having collected just 5 points so far. The difference in form is stark: Hoffenheim have won four of their last six matches across all competitions, while Mainz have managed only two wins in the same period.
Hoffenheim’s attack has been particularly impressive, averaging 2.17 goals per match and conceding just one per game. Their away form is also solid, with two wins and a draw in their last three on the road, and they tend to control possession, averaging over 54%. Mainz, on the other hand, have struggled to find the net, scoring just 0.83 goals per game recently and conceding 1.17. Their home performances have been underwhelming, with just one goal scored per match in their last three outings at the MEWA Arena.
Both teams are dealing with notable absences. Mainz will be without Nadiem Amiri, Anthony Caci, Niklas Tauer, Philipp Mwene, and Maxim Dal, all sidelined through injury or suspension. Hoffenheim are missing key attackers Andrej Kramaric and Mergim Berisha, as well as several defenders and midfielders, including Vladimir Coufal and Grischa Promel. While some injured players are edging closer to a return, neither side is expected to spring any tactical surprises.
Looking at the head to head record, Mainz have enjoyed more Bundesliga victories against Hoffenheim than any other club, with 15 wins in 37 meetings. Hoffenheim have claimed 12 victories, while 10 matches have ended in a draw. In their last five encounters, Mainz have won three, Hoffenheim one, and one match was drawn. However, the most recent meeting saw Mainz triumph 2-0, but the overall trend suggests a closely contested rivalry.
Interestingly, despite Mainz’s historical edge, the current momentum and squad depth seem to favor Hoffenheim. The market values also reflect this, with Hoffenheim’s squad worth €172.65m compared to Mainz’s €157.78m.
Let’s turn to the numbers that matter for bettors. The current betting odds for this match are:
Our AI model at NerdyTips recommends the X2 market (Hoffenheim to win or draw) as the best value, with a strong trust level of 8.5/10 and odds of 1.57. For those seeking a bolder play, the 1x2 market prediction leans towards an away win (Hoffenheim), with a confidence rating of 7.6 and odds of 2.85.
If you’re interested in total goals, the over 2.6 goals market is flagged as the best under/over bet, with a trust rating of 3.9 and odds of 1.64. Our statistical projections suggest a lively encounter, with Hoffenheim expected to edge possession (51% to 49%), take more shots (11 to 10), and create more on-target efforts (4 to 2).
Despite Mainz’s historical success in this fixture, the current form, squad depth, and attacking output all point towards Hoffenheim having the upper hand. While both coaches have faced criticism for their tactical approaches, Hoffenheim’s consistency and ability to score on the road make them worthy favorites in our Mainz vs Hoffenheim prediction.
With the odds and stats stacked in their favor, our best tip remains X2 (Hoffenheim win or draw), but those seeking higher returns may consider backing the away win outright. Expect an open game with goals, and don’t be surprised if Hoffenheim’s efficient attack makes the difference.
For more Bundesliga insights and the latest betting odds, keep following our expert analysis at NerdyTips. Good luck, and enjoy the match!
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13
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9
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10
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Hoffenheim |
12-Apr-25
2:0
| Mainz ![]() |
Mainz |
01-Dec-24
2:0
| Hoffenheim ![]() |
Mainz |
13-Apr-24
4:1
| Hoffenheim ![]() |
Hoffenheim |
26-Nov-23
1:1
| Mainz ![]() |
Mainz |
04-Mar-23
1:0
| Hoffenheim ![]() |
Hoffenheim |
14-Jan-23
2:2
| Mainz ![]() |
Hoffenheim |
10-Sep-22
4:1
| Mainz ![]() |
Mainz |
05-Feb-22
2:0
| Hoffenheim ![]() |
| 05 Dec | L |
Mainz.
|
0:1
| Borussia M.
|
| 30 Nov | L |
Freiburg.
|
4:0
| Mainz.
|
| 27 Nov | L |
Univ. Craiov.
|
1:0
| Mainz.
|
| 21 Nov | D |
Mainz.
|
1:1
| Hoffenheim.
|
| 09 Nov | L |
Frankfurt.
|
1:0
| Mainz.
|
| 06 Nov | W |
Mainz.
|
2:1
| Fiorentina.
|
| 01 Nov | D |
Mainz.
|
1:1
| Werder Breme.
|
| 29 Oct | L |
Mainz.
|
0:2
| Stuttgart.
|
| 26 Oct | L |
Stuttgart.
|
2:1
| Mainz.
|
| 23 Oct | W |
Mainz.
|
1:0
| Zrinjski.
|
| 07 Dec | Dortmund. |
- |
Hoffenheim.![]() | |
| 29 Nov | W | Hoffenheim. |
3:0 |
Augsburg.![]() |
| 21 Nov | D | Mainz. |
1:1 |
Hoffenheim.![]() |
| 08 Nov | W | Hoffenheim. |
3:1 |
RB Leipzig.![]() |
| 02 Nov | W | Wolfsburg. |
2:3 |
Hoffenheim.![]() |
| 28 Oct | D | St. Pauli. |
2:2 |
Hoffenheim.![]() |
| 25 Oct | W | Hoffenheim. |
3:1 |
Heidenheim.![]() |
| 19 Oct | W | St. Pauli. |
0:3 |
Hoffenheim.![]() |
| 03 Oct | L | Hoffenheim. |
0:1 |
1.FC Koln.![]() |
| 28 Sep | D | SC Freiburg. |
1:1 |
Hoffenheim.![]() |
Germany - Bundesliga| Team | Matches | Goals | Points | |
|---|---|---|---|---|
| 1 |
Bayern Münche | 12 | 44-9 | 34 |
| 2 |
RB Leipzig | 12 | 22-13 | 26 |
| 3 |
Borussia Dortm | 12 | 21-11 | 25 |
| 4 |
Bayer Leverkus | 12 | 28-17 | 23 |
| 5 |
1899 Hoffenhei | 12 | 25-17 | 23 |
| 6 |
VfB Stuttgart | 12 | 21-17 | 22 |
| 7 |
Eintracht Fran | 12 | 28-23 | 21 |
| 8 |
SC Freiburg | 12 | 19-20 | 16 |
| 9 |
Werder Bremen | 12 | 16-21 | 16 |
| 10 |
1. FC Köln | 12 | 21-20 | 15 |
| 11 |
Union Berlin | 12 | 15-19 | 15 |
| 12 |
Borussia Mönc | 12 | 16-19 | 13 |
| 13 |
Hamburger SV | 12 | 11-18 | 12 |
| 14 |
FC Augsburg | 12 | 15-27 | 10 |
| 15 |
VfL Wolfsburg | 12 | 14-22 | 9 |
| 16 |
1. FC Heidenhe | 12 | 10-27 | 8 |
| 17 |
FC St. Pauli | 12 | 10-24 | 7 |
| 18 |
FSV Mainz 05 | 12 | 11-23 | 6 |